New research reveals that individuals who discontinue new slimming jabs like Mounjaro or Wegovy tend to recover lost weight far faster than those who stop conventional diet and exercise programs.
Research printed in a prominent health publication points out that while overweight people frequently drop substantial amounts of their body weight while using the jabs, the mass is regained at an average rate of 0.8 kg per month after stopping.
"Individuals using these medications need to be informed of the potential of rapid weight regain when the therapy ends," cautioned researcher Dr. Susan Jebb.
This pace of regain means a return to original weight within about 18 months.
Analyzing Therapies
The study, which reviewed 37 of studies involving over 9,000 of patients, compared the results of these new drugs with conventional dieting.
Scientists emphasize that people who lose weight through diet and exercise generally have a slower weight regain—approximately 0.1 kg a month—after stopping.
The Reason for the Rapid Rebound
Nutrition scientists suggest the way of the jabs explains the accelerated weight return.
The injections imitate a natural hormone called glucagon-like peptide-1, which moderates hunger.
"Artificially providing the hormone levels far above than normal may cause the body to generate a reduced amount of its own natural hormone, and may also diminish sensitivity to its effects," said Dr. Adam Collins, a nutrition expert.
"Discontinuation of this hormone supplement results in appetite is no longer kept in check, making excessive eating a significant risk."
A Chronic Issue?
Medical guidelines recommend the jabs for people with weight-linked medical conditions, alongside prescribed lifestyle changes.
A number of clinicians contend that, considering the significant potential of weight regain, the therapy might need to be ongoing.
This view is reinforced by drug manufacturers, who note that the results "highlight the chronic character of excess weight," comparing it to managing diseases like hypertension.
Patient Experiences
People who have stopped the medication report a sudden return of hunger.
"It was like a switch that goes on and you become starving," described one woman.
This challenge is exacerbated if individuals have not developed sustainable dietary or behavioural changes during treatment.
Growing Interest
Recent estimates indicate that a significant number of people in the UK have tried weight-loss jabs in the past year, with desire continuing to grow.
- Adoption is more common among females compared to men.
- The 40s and 50s demographic shows the greatest level of interest.
- Many obtain the medications through private prescriptions rather than public health services.
Finally, experts caution that while these medications are potent tools for weight loss, they are not a magic fix and maintained weight loss hinges on ongoing lifestyle support.
